Causes of brain fog

Unfortunately, there are many hundreds of ways that cause brain fog.  and once brain fog has started it usually will not resolve without some intervention, this is because brain fog is a process that begins at one point and is then reinforced by itself, which makes the process continue, progressing to some of the worst brain diseases/disorders we see today.

How does brain fog start?

Brain fog can start from any chronic illness that starts the process of inflammation.

Genes that are “active” gene mutations can also start the process of brain fog.  This is because many genes are involved in the processes or cycles involved in the way that brain fog starts.

Most people, if they have symptoms or not, these days have inflammation or an underlying unresolved chronic illness.  We know this because eventually most everyone gets a disease, that’s why there are so many anti-inflammatory drugs and herbs/supplements being sold to contain inflammation.

The problem is anti-inflammatories don’t fix root cause problems; brain fog has a number of root causes as discussed previously.

So, it’s really important to factor in all of the problem, in order to stop the problem in its tracks, rather than paint over the problem relying on anti-inflammatory drugs, herbs etc.

Once your body has a chronic illness, this leads to body inflammation and left unchecked in the case of brain fog, that inflammation becomes inflammation of the brain, this is the beginning of how brain fog starts.

Typically to “create” a brain fog problem, you have to factor in some or even all of the following physical and mental problems:

• Anxiety (mental health)
• Depression (mental health)
• Fatigue (energy problem)
• Blood-brain barrier issues (defense, circulation, nutrient uptake and detoxification)
• Histamine problems (allergy response)
• Leaky gut (Production of LPS toxins and poor nutrient uptake/poor detoxification)
• SIBO (Gut bacteria dysbiosis)
• GI Inflammation (inflammation producing)
• Gene mutations (Messaging and control mechanisms)
• Chronic inflammation (inflammation producing)
• Chronic viral infections (inflammation producing)
• Stress reaction (inflammation producing)
• Immune problems (inflammation producing)
• Mast cell degranulation (inflammation producing)
• Neurogenic inflammation (inflammation producing)
• Cytokine production (inflammation producing)
• Mitochondrial DNA’s (inflammation producing)
• Microbiome dysbiosis (inflammation producing)
• Diminished Vagus nerve production (inflammation producing)
• Reduced gastrointestinal mobility (poor detoxification, reduction in neurotransmitters)
• Reduced Th1 cells (inflammation producing)
• Increased Th2 cells (inflammation producing)
• Methylation disruption and all of the symptoms that come with it (Poor methylation leads to hundreds of problems)

As you can see, there are many underlying causal factors that result in brain fog.

What are the major risk factors of brain fog?

Because brain fog is so complex it’s important to understand the major risk factors for the progression of the problems and why it is so important to stop the processes that cause it.

The major risk factors for brain fog are:

• Brain inflammation
• Neurodegeneration (loss of brain function)
• Autoimmune disease of the central nervous system
• Problems with methylation production
• Mental health problems
• Mental health diseases

Brain inflammation

The biggest problem with brain inflammation is diminished neuronal signaling.  In your brain you have neurons (brain cells), their job is to send signals to each other in order for your brain to function properly.

With brain inflammation, the speed at which your neurons can send those important signals slows down.  This then leads to reduced production of ATP (energy in the brain) and this leads to reduced brain function, likened to a battery running low.

Then you can’t think straight, you begin to develop brain fatigue that becomes brain fog.

Immune cytokines and brain fog / brain diseases

Cytokines serve as molecular messengers between cells mediating normal cellular processes in the body. Cytokines interact with cells of the immune system regulating various inflammatory responses to disease and infection. Cytokines are released by cells into the circulation or directly into tissue. The cytokines locate target immune cells and interact with receptors on the target immune cells by binding to them. The interaction triggers or stimulates specific responses by the target cells.

Cytokine imbalances are known to be involved in autoimmune disorders and immune dysfunction that are directly related to brain fog and or brain disease/disoders.

Common conditions associated with impaired cytokines

• Brain fog and brain diseases
• Inflammatory Bowel Disease
• Hashimotos Thyroiditis
• Depression
• Recurrent miscarriages
• Rheumatoid arthritis
• Asthma
• Eczema
• Food intolerances
• Poor immunity
• Inflammatory conditions
• Diseases associated with Cytokine activation e.g. flu, viruses etc

These are all associated with causes of brain fog and brain diseases.

Cytokines and brain fog/brain diseases/disorders

Cytokines are signaling proteins and glycoproteins that mediate and regular immunity, inflammation and hematopoiesis.  They are also involved in cell growth and differentiation, cell death, angiogenesis, normal development and neuromodulations.

Cytokines are critical to the functional both innate (cell-mediated) and adaptive (antigen-specific/humoral) immune systems.  They are known as either pro-inflammatory or anti-inflammatory.  Pro-inflammatory cytokines include interferon-gamma (INFγ), interleukin-2 (IL2) and interleukin-12 (IL12); whereas interleukin-4 (IL4) and interleukin-5 (IL5) are anti-inflammatory.

Generally, pro-inflammatory cytokines are secreted from T-helper 1 (Th1) cells and anti-inflammatory cytokines are secreted from T-helper 2 (Th2) cells.  Under normal circumstances, the Th1 and Th2 systems should be in balance, when they are not kept in check this can lead to brain fog and or brain diseases/disorders.

Cytokines and disorders of the immune system

Over-activation of either the Th1 or Th2 system can cause disease of the brain, being active even when there is no threat. When Th1 is dominating abnormally, organ-specific (the brain) autoimmune type diseases can result. On the other hand, when the Th2 system is dominating, disorders that are primarily allergy or antibody driven occur. The body becomes overly sensitive to ‘extracellular pathogens’, often reacting and producing antibodies against non‐pathogenic stimuli such as food and dust.

Health disorders associated with cytokine Th dominance

All of these disorders are associated with brain fog and or brain disease/disorders.  Immune system “balance” is critical in resolving brain fog and brain diseases/disorders.